115 Heart Blvd
Greenville, NC 27834
The Department of Cardiovascular Sciences is committed to the highest
standards of excellence and integrity in all research endeavors. Science
attempts to understand the physical world by describing, defining,
predicting and even controlling the conditions within it. Scientific
understanding is based on objective and systematic observation of events
and analytical reasoning.Experimental research designs (such as
clinical research) include random assignments of subjects to groups
that experienced carefully controlled intervention according to logic
about the effects of the drug or device being studied.
These are the various types of research designs:Clinical
Research involves the evaluation of safety and effects of a new drug,
device, biologic or preventive measure in humans comparing 2 or more
products or processes.Observational Research involves observation of people in public places.Surveys,
Questionnaires and Interviews involve statistical procedures used to
make sure the sample population properly represents the overall
population being studied.Epidemiologic Research involves
identifying risk factors for particular diseases, conditions, behaviors
or risks that result from particular causes (like environmental or
industrial agents).Case Control Research involves the comparison of subjects with a specific condition.Longitudinal
Research (prospective) involves the observation of events (diseases,
behavioral, or physiological response). Subjects are observed over an
extended period of time. In the Department of Cardiovascular
Sciences, both physicians and research nurses (coordinators) receive
extensive training in how to conduct research at East Carolina
University. They follow strict guidelines and processes established by
both the federal government and the University. Before a patient can be
enrolled in a clinical trial, each patient receives a full explanation
about the study, questions and concerns are answered, and consent is
entirely voluntary (known as Informed Consent). No patient is ever
coerced into giving consent, and if the patient declines consent, there
are absolutely no repercussions from either their physician or staff.The Department of Cardiovascular Sciences is very proud of our research program and welcomes any questions you might have.
The Department of Cardiovascular Sciences knows the importance of research in paving the way for the next generation of medical breakthroughs. That is why, in addition to our clinical research, we have a thriving basic science research environment where advances are made every day. Projects within our department further the fundamental understanding of cardiovascular diseases and therapies, down to even the cellular and molecular levels. In the lab, these projects focus on a range of topics from cardiac mitochondrial function to adult stem-cell therapies for heart repair. As the true complexity of cardiovascular diseases becomes increasingly evident, so too does the need for collaboration across scientific disciplines. Investigators within our department actively work alongside researchers throughout the Brody School of Medicine to explore all aspects of these diseases and emerging treatments.
Click the links below to learn more about these exciting research projects. Cell-based Therapy & Tissue Engineering LabPrimary Investigator: Barbara J. Muller-Borer, Ph.D. Collaborative Research, Dept. of Pharmacology & ToxicologyPrimary Investigator: Ethan J. Anderson, Ph.D.
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