Clinical and Basic Science Research at East Carolina University
The Department of Cardiovascular Sciences is committed to the highest standards of excellence and integrity in all research endeavors. Science attempts to understand the physical world by describing, defining, predicting and even controlling the conditions within it. Scientific understanding is based on objective and systematic observation of events and analytical reasoning.Experimental research designs (such as clinical research) include random assignments of subjects to groups that experienced carefully controlled intervention according to logic about the effects of the drug or device being studied.
These are the various types of research designs:
Clinical Research involves the evaluation of safety and effects of a new drug, device, biologic or preventive measure in humans comparing 2 or more products or processes.
Observational Research involves observation of people in public places.
Surveys, Questionnaires and Interviews involve statistical procedures used to make sure the sample population properly represents the overall population being studied.
Epidemiologic Research involves identifying risk factors for particular diseases, conditions, behaviors or risks that result from particular causes (like environmental or industrial agents).
Case Control Research involves the comparison of subjects with a specific condition.
Longitudinal Research (prospective) involves the observation of events (diseases, behavioral, or physiological response). Subjects are observed over an extended period of time.
In the Department of Cardiovascular Sciences, both physicians and research nurses (coordinators) receive extensive training in how to conduct research at East Carolina University. They follow strict guidelines and processes established by both the federal government and the University. Before a patient can be enrolled in a clinical trial, each patient receives a full explanation about the study, questions and concerns are answered, and consent is entirely voluntary (known as Informed Consent). No patient is ever coerced into giving consent, and if the patient declines consent, there are absolutely no repercussions from either their physician or staff.
The Department of Cardiovascular Sciences is very proud of our research program and welcomes any questions you might have.
Basic Science Research
The Department of Cardiovascular Sciences knows the importance of research in paving the way for the next generation of medical breakthroughs. That is why, in addition to our clinical research, we have a thriving basic science research environment where advances are made every day.
Projects within our department further the fundamental understanding of cardiovascular diseases and therapies, down to even the cellular and molecular levels. In the lab, these projects focus on a range of topics from cardiac mitochondrial function to adult stem-cell therapies for heart repair. As the true complexity of cardiovascular diseases becomes increasingly evident, so too does the need for collaboration across scientific disciplines. Investigators within our department actively work alongside researchers throughout the Brody School of Medicine to explore all aspects of these diseases and emerging treatments.